Inclusion criteria
Preeclamptic women with ages 14 – 45 years old, blood pressure ≥ 140/90, and also with proteinuria
≥300mg/24hrs urine collection were included. Preeclamptic patients with blood pressure ≥ 160/110 or/and
proteinuria ≥ 1g/ 24 hours urine collection or/and presence of papillodema were taken as severe preeclamptic
cases, while preeclamptic patients with blood pressure 159/109 – 140/90, proteinuria 0.3 to 1g/ 24 hours urine
collection and absence of papillodema taken as mild preeclampsia.
Exclusion criteria
Pregnant women with pre-gestational diabetes mellitus, primary or secondary lipid disorders, severe
anemia, those suffer from any other hematological or endocrine disorders were excluded. Questionnaires were
filled and blood samples were obtained for measurement of laboratory parameters by using chemical and
hematological analyzers. Data were analyzed by SPSS program version 20.
Ethical approval
The review board and ethics committee of University of West Kordufan for Medical Education and
Research approved the study protocol and informed consents were taken from all the participants.
RESULTS
Figure 1 show the ages of participants which were 14 – 20 (28.5%), 21 – 25 (21.5%), 26 – 30 (30.9%) and > 30
(19.1%). Figure 2 shows the parity of the study group, primiparous (45.2%), multiparous (34.7%) and grand
multiparous (19.2%). From the entire participants, (76%) have severe preeclampsia and (24%) have mild
preeclampsia.
Characteristics and description of the study group
Table 1 shows the characteristics and description of the study group. The occupations of the participants
were teacher (2.4%), employee (2.4%), farmer (7.1%) and housewife (88.1%). The study group ages at time of
marriage per year were 14-20 (73.8%), 21-25 (14.3%), 26-30 (7.1%) and > 30 (4.8%) years old. Regarding gestational
ages at onset of preeclampsia per week they were 20 - 24(9.5%), 24+1 –28(7.1%), 28+1 – 32(19%), 32+1 – 36(40.5%)
and > 36(23.9%). The participants having blood pressure ≥ 160/110 represent (42.9%) and those having blood
pressure 159/109 – 140/90 were (57.1%)
Laboratory findings of study group
Table 2 shows the laboratory findings of the participants. Proteinuria (dipstick) for the study group were +
(19%), ++ (42.9%) and +++ (38.1%), and there was significant elevation in the cases of severe preeclampsia with ++
and +++ (P=0.052). (52.4%) of the participants have proteinuria from 0.3 – 1 and (47.6%) have proteinuria > 1 with
significant elevation in sever preeclampsia compared to mild preeclampsia (P=0.002). Plasma total protein for
the study group was (33.3%) normal (66.7%) high and no participant having low plasma total protein and there
was no significant difference between sever and mild cases. Hemoglobin level for participants was (81%) low,
(19%) normal and no patient have high hemoglobin level and there was no significant difference between sever
and mild cases. For TWBCs, (83.3%) of participants their TWBCs were normal, (16.7%) have leucocytosis and no
one have low TWBCs count, with no significant difference between sever and mild patients. Regarding the RBCs
for study group, (11.9%) have low count, (85.7%) their RBCs were in normal range, while (2.4%) have high RBCs
count and there was no significant difference between sever an mild cases. Concerning PLT, (38.1%) low PLT,
(57.1%) normal PLT count and (4.8%) high PLT count with no significant difference between sever and mild
cases. For lymphocytes, (31%) of the participants have normal lymphocytes (69%) have high lymphocytes and no
one have low lymphocytes count with no significant difference between sever and mild preeclamptic patients.
(2.4%) of entire participants have low MCV, no normal MCV, while (97.6%) have high MCV and there was no
significant difference between sever and mild cases. For MCH, (92.9%) of the participants have low MCH, (2.4%)
have normal MCH and (4.8%) have high MCH, with no significant difference between sever an mild cases in all.
38.1%
Mild Sever
Age/year
Mild Sever
Parity
23.8%
21.4%
16.7%
23.8%
14.3%
14.3%
11.9%
7.1%
7.1%
7.1%
4.8%
4.8%
4.8%
Primiparous
Multiparous
Grand multiparous
Ages (> 30)
Ages (26-30)
Ages (21-25)
Ages (14-20)
Figure 1. Ages of the study group
Figure 2. Parity of the study group
Citation: Hobiel Ahmed HA and Suleiman Amin MA. 2019. Hematological and selected biochemical indices in preeclamptic pregnant women attending Elnihoud
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