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Volume 11 (1); January 25, 20201


Review

Stem cells: source and therapeutic application.

Fesseha H.

J. Life Sci. Biomed., 11(1): 01-12, 2020; pii:S225199392100001-11

DOI: https://dx.doi.org/10.51145/jlsb.2021.1

Abstract

Introduction. Stem cells spontaneously renovate themselves into a specialized adult cell type. These defining characteristics have a lot of advantages in stem cell-based therapies. The two key types of stem cells are pluripotent and multipotent, which can differentiate to various cells in the adult body and only restricted cell types, respectively. Currently, Stem cell treatment is now very promising, bringing tremendous promise for medical medicine by offering treatments for untreatable disorders. Regulated laboratory steps of stem cell development and derivation are needed to ensure the genesis of stem cells. Besides, before implementation, stem cells should undergo quality control and teratoma development tests, which are necessary to determine their properties. While progress in the clinical use of stem cells is being made, there are still barriers to stem cell therapy being embraced internationally. Aim. The biology, cell sources, characteristics, differentiation, therapeutic application potential and manipulation achievement are discussed. 

Keywords: Differentiation, Therapeutic application, Stem cells, Pluripotency, Source

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